Scientist- CBA

Job Description

Scientist,CBA

The Jackson Laboratory | Bar Harbor ME

About the Role

The Jackson Laboratory is
seeking
a highly motivated Scientist to join our Core Scientific Services team within the Metabolic Phenotyping Core. This position provides scientific
expertise
, technical leadership, and operational support for advanced
in vivo
metabolic phenotyping technologies and services that enable
cutting-edge
biomedical research across diverse scientific programs, including obesity, diabetes,
MASH
,

atherosclerosis
and muscle biology.

The Scientist will partner with investigators, research staff, and cross-functional teams to develop,
optimize
, and implement scientific solutions that support internal and external research initiatives. This individual will
leverage
technical
expertise
to evaluate emerging technologies, troubleshoot complex scientific challenges, ensure quality standards, and deliver exceptional scientific
service
to a broad research community.

The ideal candidate is an independent scientist with strong technical
proficiency
, a collaborative mindset, and a passion for enabling scientific discovery through shared resources and innovative technologies.

Key Responsibilities

Design, develop,
optimize
, and execute
in vivo
metabolic phenotyping workflows, assays, and methodologies that support core service operations and research
objectives
.

Analyze, interpret, and communicate experimental data and results to diverse scientific audiences.

Evaluate, implement, and
validate

new technologies
, equipment, and workflows to enhance service capabilities and operational efficiency.

Develop and
maintain
standard operating procedures (SOPs), quality control processes, and best practices to ensure data integrity and reproducibility.

Troubleshoot complex technical and scientific issues and
identify
innovative solutions to improve performance and outcomes.

Collaborate with multidisciplinary teams to support research initiatives, grant applications, publications, and strategic projects.

Train, mentor, and
provide
technical guidance to research staff, students, and laboratory personnel.

Contribute to the strategic growth and continuous improvement of core scientific services through process optimization and adoption of emerging technologies.

Maintain compliance with institutional, regulatory, and safety requirements.

Knowledge, Skills, and Abilities

Demonstrated
expertise
in one or more of the following areas: obesity, metabolic disease (including type
-
2 diabetes
, MASH,
atherosclerosis), aging, skeletal muscle biology, or islet (β-cell) biology.

Expertise
in preclinical pharmacology, including
in vivo
efficacy, execution, analysis, and interpretation.

Proficiency with indirect calorimetry / metabolic cage systems (e.g., Sable Systems
Promethion
, or equivalent), Body
co
m
position
analysis using
EchoMRI
, DEXA, and/or
microCT
, core metabolic phenotyping assays, including glucose tolerance tests (GTT), insulin tolerance tests (ITT), and mixed-meal tolerance tests (MMTT
)
, treadmill
-based endurance capacity testing.

Hyperinsulinemic
-euglycemic and
hyperglycemic
clamp techniques.

Muscle biology experience is a strong plus.

Desirable:

Surgical
proficiency
in transplantation techniques, including grafting under the kidney capsule

Minimum Qualifications

Master's degree in biology
, Biomedical Sciences, Genetics, Molecular Biology, Biotechnology, Bioinformatics, or a related scientific discipline
required
; Ph.D. preferred.

Four (4) or more years of relevant scientific experience supporting research programs, scientific services, core facilities, biotechnology, pharmaceutical, academic, or contract research environments.

Experience with advanced laboratory technologies, instrumentation, and scientific data analysis.

Track record
of scientific achievement
demonstrated
through research contributions, publications, presentations, technology implementation, or project leadership preferred.

Why Join Us

As part of Core Scientific Services, you will play a vital role in advancing research across multiple scientific disciplines while working with
state-of-the-art
technologies and a collaborative community of scientists. This position offers the opportunity to influence research outcomes, drive innovation, and help enable discoveries that improve human health.

Pay Range: $85987 - $143962 per year, dependent upon experience.
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit

www.jax.org
​​​​​​​
.
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Minimum Qualifications

Master's degree in biology , Biomedical Sciences, Genetics, Molecular Biology, Biotechnology, Bioinformatics, or a related scientific discipline required ; Ph.D. preferred. Four (4) or more years of relevant scientific experience supporting research programs, scientific services, core facilities, biotechnology, pharmaceutical, academic, or contract research environments. Experience with advanced laboratory technologies, instrumentation, and scientific data analysis. Track record of scientific achievement demonstrated through research contributions, publications, presentations, technology implementation, or project leadership preferred. Why Join Us As part of Core Scientific Services, you will play a vital role in advancing research across multiple scientific disciplines while working with state-of-the-art technologies and a collaborative community of scientists. This position offers the opportunity to influence research outcomes, drive innovation, and help enable discoveries that improve human health. Pay Range: $85987 - $143962 per year, dependent upon experience.